Open browser-tab dump.
~ Steve Cooksey, a T2 diabetic who undertook his own resistant starch experiment and, just a couple of days ago, reported on the amazing blood glucose regulation of a T1 also trying RS, is still at it. He’s done a “flex test” with a big baked potato.
Punchline, but do read the short post: Typically, he’ll hit 260+ at the one hour mark after eating a big tater, but this time, only got to 160ish, 100 mg/dl less, and it continued to go down to normal ranges more quickly. I’d like to see him add 2-4T to warm mashed potatoes for another test.
~ All this cheap potato starch or green plantain flour (or any number of other high RS starches) to feed gut bacteria is all bullshit, right? OK, well then how come some people are betting millions on getting a patented prescription intervention to essentially do the same thing you can do every day in your own kitchen?
BROOMFIELD, Colo., Dec. 16, 2013 /PRNewswire/ — microbiome TherapeuticsTM LLC, (MBT) today announced completion of a $1.3 million bridge financing. It is intended to support completion of the company’s two ongoing clinical studies and preparations for further clinical trials of lead product NM504, a microbiome modulator in development for type 2 diabetes and prediabetes. The bridge financing was led by current investor BVM Capital, who was joined in the round by other existing MBT investors.
“We welcome our investors’ continuing support as we wrap up our pilot studies of NM504 and prepare for the next phase of clinical trials,” noted Steve Orndorff, CEO of microbiome Therapeutics. “”Growing evidence supports a role for the gut microbiome in a range of disorders, and interest in the therapeutic potential of microbiome modulators is soaring. These additional funds will enable us to complete our ongoing studies and prepare for our next set of clinical trials. We expect to report results from the current studies soon, prior to the launch of a significant Series B financing during 2014.”
NM504 is being studied in two placebo-controlled, double-blinded, proof of concept trials. The first is assessing its ability to alter the gastrointestinal (GI) microbiome to enhance insulin sensitivity and fasting blood glucose levels in prediabetic individuals. The second is testing the utility of NM504 in combination with metformin in diabetes patients with adverse GI effects. NM504 has previously demonstrated the potential to mitigate these adverse effects.
MBT is developing microbiome modulators that alter bacterial populations and their environment in the GI tract to address serious health conditions. The company’s microbiome modulators are designed to act on multiple factors in the GI environment, augmenting the growth of targeted desirable bacterial strains and discouraging the growth of others. NM504 is formulated to promote microbiome shifts that positively affect metabolism and weight.
~ The Surprising Healing Qualities … of Dirt. All while richish mothers and fathers are literally killing their children socially and physically by their ignorant helicoptering over every single aspect of their children’s lives—from who they play with and what goes on, to their anti-bacterial jihad. …My judgment? “Regurgitators” who don’t know anything, trust everything with letters after name and growing bank account.
Impressed by the growing evidence that our health depends on healthy soil, my “dirty thoughts” have turned to action. I now tell my patients that food grown in well-treated soil might offer distinct advantages when it comes to scoring the best nutrients and building a healthy immune system.
~ Folks, now seriously. How many of you have benefited from my and Tim’s hundreds of hours of collaboration and the subsequent 50 posts and thousands of comments on resistant starch? In the spirit and season of giving, can’t you spare something like 10-25 bucks for a pretty cool experiment? It’s a family of 4 who wants to get their gut biome tested before, and then after administration of resistant starch: to actually see the effect on the bacterial mix and quantities of good to bad, if there truly is one. Aren’t you curious to the tune of $25?
I know you get hit up all the time and I agree, it gets cumbersome and annoying. But so many have commented about great benefits they have received and others, about how potentially game-changing this is.
Please give me a Christmas gift that I have never asked for in 10 years of blogging and almost 3,800 posts…and give it to them. Please don’t count on others.
Those others are indeed: you.
~ Joyeux Noel et une Bonne Année à vous et les vôtres.
A fond memory I’ll never forget is seeing this at original airing sometime in the mid 70s. David Bowie and Bing Crosby. A treasure.
I’ll be in touch.