I’ve previously blogged about my use of a new high-dose probiotic called Elixa. It’s not one you take all the time, but a 6-day course you take now & then. I’ve written about it twice before:
- Gut Bugs, Probiotics, Prebiotics…And how our microbes make us who we are
- FODMAP Prebiotic Arms Dealing, Probiotic Mercenaries, and Uganda
One thing its creator, Karl Seddon, is happy to do is to interact personally with customers via email. For instance, one woman had some flu-like symptoms, detailed here, here, and here. That last one is Karl’s input.
Feel free to contact me directly to discuss your theory further, as it is interesting indeed – as far as acidosis-susceptible individuals are concerned.
However…. while there is a logical chain linking it all together on paper, I happen to have had clinical experience with patients suffering from several conditions, 3 of which could relate (for purposes of discussion) to this type of situation: bacteremia, metabolic acidosis (including lactic acidosis post-surgery for ileal pouch), and Jarisch-Herxheimer response to IV antifungals.
The ‘hot/flushed’ symptom you have listed is a typical presentation of Jarisch-Herxheimer and would differentiate the diagnosis away from investigations of acidosis or hyperlactemia.
While the J-H response is an indicator that large amounts of non-beneficial microorganisms are experiencing cell lysis (a GOOD thing), I can fully appreciate that it may be a disconcerting experience. In any case, I think she will make the right choice to discontinue it if the response is this acute.
The unfair irony is that certain people who can benefit from probiotics, will experience this type of Jarisch-Herxheimer response much more than others. (I believe this is what you are referring to as ‘die-off’).
Very un-sales-pitch like, one might say.
In another testimonial, commenter ‘jonw’ writes:
I used a six-pack and noted effects, meanwhile avoiding influence by reading any accounts here. Took caps in mornings on empty stomach, followed by breakfast. First two days: incredible amount of noisy gut-churning, bad diarrhea. Energy levels good, workout performance great, strangely low appetite. (I ate anyway just by habit and it’s recommended on the label, but def less than normal.) Diarrhea cleared by third day, still feeling fine otherwise through the rest of the doses. Probably lost some weight. A weird effect – beer is not appetizing to me now – couldn’t be bothered to finish my 12oz IPA.
So I guess the colony should be established by now… not sure if it had any permanent effects… hard to say.
I had similar “TMI” issues with the first 2 rounds of the 4-rounds I’ve taken over about the last 3 months. Best of all the “meh” aspect of appetite persists down here in off-the-grid Baja, on a diet of mostly beans, fruit, eggs, dairy, fish. Weight is normalizing at a fairly good pace—noted by drawstring pull on swimming trunks. I’m getting rather optimistic about putting up a body-comp pic in a month or so.
Your feedback is much appreciated. Thank you! This transient effect on intestinal motility is quite common. Rarely to the degree that you experienced, but certainly a handful of people have reported similar. I have also noted it in several people during the development phase of Elixa (at higher dosages and higher water consumption with the dose).
It’s related to the fortress-5 encapsulation process. The body is detecting (via chemical receptors in the stomach) that the unknown items that have just been swallowed do not seem to be digestible, so it chooses the best course of action to be to increase rate of gastric emptying and peristaltic contractions in the small intestine. No doubt an evolved reaction to when we accidentally ate bits of bone, teeth, small stones, etc. For purposes of delivering Elixa to the large intestine as quickly as possible, I aimed (successfully) to take advantage of this response.
The macronutrient attributes of the food we consume determine our intestinal motility. Fats and protein are intentionally retained in the stomach for longer (for emulsification and protease action, respectively), while carbohydrates are funneled on through to the duodenum, fairly rapidly. Non-digestible oligosaccharides and hypertonic solutions; even more so.
If you get a chance, send me an email in a few days to give me an update on your steady-state results. Thanks!
Very interesting indeed. Designing a probiotic not so much as to be resistant to digestion, but designing it in such a way that the stomach sees it as a foreign object and sends it on its way faster.
So great, personal customer service, and from “the guy” himself. So, if that all impresses you and it probably should given for what so often passes as no direct answers to real questions or input, then maybe you want to give Elixa a look. Just click here.